Precisely what is NMN?
NMN stands for nicotinamide mononucleotide, a naturally sourced molecule seen in all species. Around the molecular level, this is a ribonucleotide, a simple structural unit with the nucleic acid RNA. It is made up of nicotinamide group, a ribose, as well as a phosphate group.
NMN is really a precursor of nicotinamide adenine dinucleotide (NAD+), a molecule that could be valuable in reducing some aspects of aging. NAD+ serves many critical functions within our cells, like electron transport, cell signaling, and DNA repair.
Accumulating evidence shows that as we get older, our numbers of NAD+ decline, increasing our probability of age-related diseases.
That’s where the NAD+ precursor NMN also comes in. Some researchers believe when we can restore that lost NAD+, we could not merely slow down aging but in addition delay various age-related diseases. Regardless of whether restoring NAD+ metabolism in humans will slow aging or support healthy longevity is still an unanswered question, although the animal information is promising.
What foods contain NMN?
NMN are available naturally in foods including avocado, broccoli, cabbage, cucumber, and edamame. This is how much NMN is found in some common foods.
While such foods are rich in nutrition, dietary NMN supplements can be found. These supplements typically are available in doses which can be between 100 – 500 mg, although an ideal dose has not determined in people.
Fasting and caloric restriction also apparently increase NAD+ levels and boost the activity of sirtuins, aka the longevity genes. It is strongly recommended that their activity relies on the use of NAD+. In mice, fasting boosted NAD+ levels and sirtuin activity, and yes it appears to be slow down aging.
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